| Use of Integra artificial skin is associated with decreased length of stay for severely injured adult burn survivors. | |
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MedLine Citation:
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PMID: 12352131 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Mortality and length of stay (LOS) of survivors was examined retrospectively in 270 adults with acute burns > or =20% of body surface area to determine the effect of Integra Dermal Regeneration Template treatment on outcome. No difference in mortality was found between patients who received Integra (30%; n = 43) and patients who did not (30%; n = 227). Surviving Integra patients (n = 30) stayed longer, but they were more extensively injured than survivors who did not receive Integra (n = 158), and therefore longer hospitalizations were expected. In a subgroup analysis, mean LOS of Integra patients with two or more mortality risk factors (age > 60 years, burn size >40% body surface area, or inhalation injury; n = 15) was 63 days compared with 107 days in patients with two or more risk factors (n = 29) who did not receive Integra ( =.014). Integra use in severely injured burned adults was associated with a marked decrease in LOS. |
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Authors:
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Colleen M Ryan; David A Schoenfeld; Maryanne Malloy; John T Schulz; Robert L Sheridan; Ronald G Tompkins |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Journal of burn care & rehabilitation Volume: 23 ISSN: 0273-8481 ISO Abbreviation: J Burn Care Rehabil Publication Date: 2002 Sep-Oct |
Date Detail:
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Created Date: 2002-09-27 Completed Date: 2002-11-19 Revised Date: 2006-08-15 |
Medline Journal Info:
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Nlm Unique ID: 8110188 Medline TA: J Burn Care Rehabil Country: United States |
Other Details:
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Languages: eng Pagination: 311-7 Citation Subset: IM |
Affiliation:
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Department of Surgery, Sumner Redstone Center, Massachusetts General Hospital, Boston, MA 02114, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Aged, 80 and over Biocompatible Materials / therapeutic use* Burns / mortality, pathology, therapy* Chondroitin Sulfates Collagen Female Humans Length of Stay* Male Middle Aged Outcome Assessment (Health Care) Retrospective Studies Survivors* Time Factors Trauma Severity Indices |
| Chemical | |
Reg. No./Substance:
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0/Biocompatible Materials; 0/integra artificial skin; 9007-28-7/Chondroitin Sulfates; 9007-34-5/Collagen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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