Document Detail

Use of grape polyphenols for promoting human health: a review of patents.
MedLine Citation:
PMID:  22316271     Owner:  NLM     Status:  MEDLINE    
We presently discuss the use of grape polyphenols for promoting human health and disclose recent patents on the subject. The biological effects of grape polyphenols in human and experimental models demonstrate antioxidant properties closely associated with the maintenance of endothelial function, increase in antioxidant capacity, protection against LDL oxidation and neuroprotective effects. Recent patents regarding grape polyphenols show a tendency to return to natural products with a minimum use of severe extraction processes and organic solvents. Moreover, the recent patents regarding human health show more pharmaceutical use of grape juice and other polyphenol-rich products. The application of such products in clinical trials as a substitute or co-adjuvant with drugs may be useful in future research.
Andréa P B Gollücke; Daniel A Ribeiro
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Recent patents on food, nutrition & agriculture     Volume:  4     ISSN:  1876-1429     ISO Abbreviation:  Recent Pat Food Nutr Agric     Publication Date:  2012 Apr 
Date Detail:
Created Date:  2012-03-27     Completed Date:  2012-07-27     Revised Date:  2012-10-16    
Medline Journal Info:
Nlm Unique ID:  101526178     Medline TA:  Recent Pat Food Nutr Agric     Country:  United Arab Emirates    
Other Details:
Languages:  eng     Pagination:  26-30     Citation Subset:  IM    
Hexalab/Unisantos and Nutrition Department - Catholic University of Santos. Av. Conselheiro Nébias, 300. Santos-SP 11015-002, Brazil.
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MeSH Terms
Antioxidants / therapeutic use*
Cholesterol, LDL
Endothelium, Vascular
Health Promotion
Neuroprotective Agents
Patents as Topic*
Plant Extracts / therapeutic use*
Polyphenols / therapeutic use*
Vitis / chemistry*
Reg. No./Substance:
0/Antioxidants; 0/Cholesterol, LDL; 0/Neuroprotective Agents; 0/Plant Extracts; 0/Polyphenols

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