Document Detail


Use of the Exercise Treadmill Test for the Assessment of Cardiac Risk Markers in Adults Infected with HIV.
MedLine Citation:
PMID:  23015380     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Background: Despite the association between HIV and coronary artery disease (CAD), there are no specific recommendations for the cardiovascular evaluation of the HIV-infected population. Besides being a tool for the evaluation of CAD, the exercise treadmill test (ETT) provides insights into functional capacity and autonomic function, which have been frequently affected in HIV infection, and thus may be useful in this setting. METHODS: Forty-nine HIV-infected individuals without known CAD underwent ETT. Peak oxygen consumption during exercise (VO2 peak), functional capacity (in metabolic equivalents [METs]), exercise-induced ischemia, chronotropic incompetence (CI) and abnormal heart rate recovery (HRR) after exercise were studied. RESULTS: VO2 peak was 31.4±4.8 mL/kg/min and functional capacity was 9.2±1.6 MET. CI was observed in 30.6%, and 10.2% had abnormal HRR. VO2 peak was lower in women and inversely correlated with age and body mass index. None of the patients displayed ischemic changes. CONCLUSION: Although functional capacity was good, risk markers such as CI and abnormal HRR were not infrequent. This study identifies a subgroup of HIV-infected patients-the older, overweight, or obese-who may have higher risk and deserve cardiovascular screening with the ETT.
Authors:
Andrea De Lorenzo; Vanderson Meirelles; Felippe Vilela; Fernando Cesar C Souza
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-9-26
Journal Detail:
Title:  Journal of the International Association of Physicians in AIDS Care (Chicago, Ill. : 2002)     Volume:  -     ISSN:  1545-1097     ISO Abbreviation:  J Int Assoc Physicians AIDS Care (Chic)     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-9-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101185740     Medline TA:  J Int Assoc Physicians AIDS Care (Chic)     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
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