Document Detail

Use of Electrical Coupling Information (ECI) in AF catheter ablation: A prospective randomized pilot study.
MedLine Citation:
PMID:  23059130     Owner:  NLM     Status:  Publisher    
BACKGROUND: Catheter contact is important for radiofrequency (RF) ablation. Local electrical catheter-to-tissue coupling has been described as a tool to objectively measure contact. OBJECTIVE: We hypothesized that pulmonary vein isolation (PV) ablation using electrical coupling information (ECI) would yield higher rates of PV isolation (PVI) than an approach without ECI. METHODS: Forty patients with atrial fibrillation were prospectively included. In each patient, one pair of PVs was randomly chosen to be encircled with ECI available while the other pair was encircled without use of ECI. RESULTS: The rate of PVI was significantly higher in PVs encircled with ECI available (58% vs. 30%; p=0.024). PV encircling with coupling resulted in slightly longer procedure (26.5 [IQR 22 - 32.5] vs. 23.5 [IQR 19 - 26.5] min; p=0.019), fluoroscopy (9.0 [IQR 6 - 12] vs. 6.9 [IQR 4 - 8.6] min; p=0.011 and RF times (20.0 [IQR 16.5 - 23.5] vs. 17.3 [IQR 15.1 - 20.6] min; p=0.015). For non-isolated PVs the coupling group had significantly fewer gaps (3.0 [IQR 1.8 - 7] vs. 6.0 [IQR 4 - 11]; p = 0.021); gap mapping/closure needed shorter procedure (9.0 [IQR 4 - 16] vs. 13.0 [IQR 11 - 21] min; p=0.04), fluoroscopy (3.9 [IQR 2 - 7.1] vs. 6.0 [IQR 4.6 - 7.9] min; p=0.038) and RF times (1.9 [IQR 0.9 - 5] vs. 5.2 [IQR 3.3 - 8.6] min; p=0.016). CONCLUSION: Use of ECI improved lesion deployment measured as higher rates of PVI after anatomical encircling. For non-isolated PVs, fewer gaps and faster gap closure were found using ECI.
Thomas Gaspar; Haris Sih; Gerhard Hindricks; Charlotte Eitel; Philipp Sommer; Simon Kircher; Sascha Rolf; Arash Arya; Liane Teplitsky; Christopher Piorkowski
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-10-8
Journal Detail:
Title:  Heart rhythm : the official journal of the Heart Rhythm Society     Volume:  -     ISSN:  1556-3871     ISO Abbreviation:  Heart Rhythm     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101200317     Medline TA:  Heart Rhythm     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012. Published by Elsevier Inc.
University of Leipzig, Heart Center, Dept. of Electrophysiology, Leipzig, Germany. Electronic address:
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Working memory development in monolingual and bilingual children.
Next Document:  Percutaneous Epicardial Ventricular Tachycardia Ablation After Non-Coronary Cardiac Surgery or Peric...