Document Detail

Use of drug-eluting versus bare-metal stents in ST-segment elevation myocardial infarction.
MedLine Citation:
PMID:  19901420     Owner:  NLM     Status:  MEDLINE    
The development of drug-eluting stents (DES) is one of the critical milestones in the advances of interventional cardiology. However, clinical stent thrombosis still poses a serious potential complication. In acute ST-segment elevation myocardial infarction (STEMI), acute total vessel occlusion has a larger thrombus burden, and the use of DES in this particular setting raises safety concerns. Published data from randomized, controlled studies, observational studies and recently published meta-analyses mostly support the safety of DES use in acute STEMI. However, these studies have limited study populations and follow-up periods, so the long-term safety of DES in the setting of STEMI is still unclear, and careful consideration should be given in clinical decision-making. In this article we reviewed the findings of randomized and nonrandomized trials on the use of drugeluting versus bare-metal stents in the setting of acute STEMI.
Shih-fan Chen; Adel El-Bialy; Ray Matthews; Leonardo Clavijo
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The Journal of invasive cardiology     Volume:  21     ISSN:  1557-2501     ISO Abbreviation:  J Invasive Cardiol     Publication Date:  2009 Nov 
Date Detail:
Created Date:  2009-11-10     Completed Date:  2010-02-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8917477     Medline TA:  J Invasive Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  E206-12     Citation Subset:  IM    
Los Angeles County Hospital/University of Southern California Medical Center, Department of Cardiovascular Medicine, Los Angeles, CA, USA.
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MeSH Terms
Acute Disease
Angioplasty, Transluminal, Percutaneous Coronary / methods*
Drug-Eluting Stents*
Myocardial Infarction / diagnosis,  therapy*
Reg. No./Substance:

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