Document Detail

Use of the Cytobrush for Papanicolaou smear screens in pregnant women.
MedLine Citation:
PMID:  8708804     Owner:  NLM     Status:  MEDLINE    
A prospective, randomized clinical trial was conducted to study the safety and efficacy of the Cytobrush for Papanicolaou smear screens in 252 pregnant women. Two groups-Ayre spatula plus Cytobrush and Ayre spatula plus cotton swab-were compared. There was a higher incidence of spotting with each of the three devices as compared with studies of nonpregnant women. The highest incidence of spotting at time of exam occurred with the Cytobrush; however, this spotting was not clinically significant. Eleven first-trimester women experienced a pregnancy loss; five of these losses were due to a hydatidiform mole or missed abortion that occurred before the exam. Six women (2%) aborted spontaneously compared with a 10% incidence reported in the literature. It was concluded that all three devices are safe for use in pregnancy. In addition, the most adequate screen for retrieval of squamous epithelial cells was found to be the Ayre spatula, while the Cytobrush proved most effective for retrieval of endocervical epithelial cells.
J C Foster; H L Smith
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial    
Journal Detail:
Title:  Journal of nurse-midwifery     Volume:  41     ISSN:  0091-2182     ISO Abbreviation:  J Nurse Midwifery     Publication Date:    1996 May-Jun
Date Detail:
Created Date:  1996-09-10     Completed Date:  1996-09-10     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0365647     Medline TA:  J Nurse Midwifery     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  211-7     Citation Subset:  IM; N    
College of Nursing, University of Utah, Salt Lake City 84112, USA.
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MeSH Terms
Chi-Square Distribution
Cross-Over Studies
Equipment Design
Prospective Studies
Vaginal Smears / adverse effects,  instrumentation*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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