Document Detail

Use of coronary physiology in the catheterization laboratory to guide treatment in patients with coronary artery disease.
MedLine Citation:
PMID:  21110144     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Fractional flow reserve (FFR) is an invasive pressure-derived index of epicardial stenosis severity used in the catheterization laboratory to assess the hemodynamic significance of coronary lesions when non-invasive functional assessment has either not been performed or is inconclusive. The rationale for the use of FFR is that coronary angiography cannot accurately predict the hemodynamic significance of lesions with diameter stenosis <90% and that there is a large body of literature supporting the use of FFR for directing coronary revascularization. Specifically, in patients with stable angina and low-risk acute coronary syndromes, revascularization with either percutaneous coronary intervention (PCI) or coronary artery bypass graft (CABG) surgery should be deferred for epicardial coronary stenoses with an FFR > 0.80. Use of FFR to direct coronary revascularization should continue to increase as it has been demonstrated to improve outcomes and reduce cost.
Michael McDaniel; Habib Samady
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Current treatment options in cardiovascular medicine     Volume:  13     ISSN:  1534-3189     ISO Abbreviation:  Curr Treat Options Cardiovasc Med     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-01-11     Completed Date:  2011-07-14     Revised Date:  2013-07-25    
Medline Journal Info:
Nlm Unique ID:  9815942     Medline TA:  Curr Treat Options Cardiovasc Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  35-45     Citation Subset:  -    
Department of Medicine, Emory University School of Medicine, Suite F606, 1365 Clifton Road, Atlanta, GA, 30322, USA.
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