Document Detail

Use of central venous catheter and peripheral venous catheter as risk factors for nosocomial bloodstream infection in very-low-birth-weight infants.
MedLine Citation:
PMID:  20175683     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To describe the relationship between the use of central and peripheral venous catheters and the risk of nosocomial, primary, laboratory-confirmed bloodstream infection (BSI) for neonates with a birth weight less than 1,500 g (very-low-birth-weight [VLBW] infants). METHODS: Cox proportional hazard regression analysis with time-dependent variable was used to determine the risk factors for the occurrence of BSI in a cohort of VLBW infants. We analyzed previously collected surveillance data from the German national nosocomial surveillance system for VLBW infants. All VLBW infants in 22 participating neonatal departments who had a complete daily record of patient information were included. RESULTS: Of 2,126 VLBW infants, 261 (12.3%) developed a BSI. The incidence density for BSI was 3.3 per 1,000 patient-days. The multivariate analysis identified the following significant independent risk factors for BSI: lower birth weight (hazard ratio [HR], 1.1-2.2), vaginal delivery (HR, 1.5), central venous catheter use (HR, 6.2) or peripheral venous catheter use (HR, 6.0) within 2 days before developing BSI, and the individual departments (HR, 0.0-4.6). CONCLUSIONS: After adjusting for other risk factors, use of peripheral venous catheter and use of central venous catheter were significantly related to occurrence of BSI in VLBW infants.
Christine Geffers; Anne Gastmeier; Frank Schwab; Katrin Groneberg; Henning R?den; Petra Gastmeier
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Infection control and hospital epidemiology : the official journal of the Society of Hospital Epidemiologists of America     Volume:  31     ISSN:  1559-6834     ISO Abbreviation:  Infect Control Hosp Epidemiol     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-03-02     Completed Date:  2010-06-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8804099     Medline TA:  Infect Control Hosp Epidemiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  395-401     Citation Subset:  IM; N    
National Reference Center for the Surveillance of Nosocomial Infections, Institute for Hygiene and Environmental Medicine, Charit?-University Medicine Berlin, Berlin, Germany.
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MeSH Terms
Bacteremia* / diagnosis,  microbiology
Catheterization, Central Venous / adverse effects*,  utilization
Catheterization, Peripheral / adverse effects*,  utilization
Catheters, Indwelling / adverse effects
Cross Infection / diagnosis*,  microbiology,  virology
Fungemia* / diagnosis,  microbiology
Infant, Newborn
Infant, Very Low Birth Weight
Proportional Hazards Models
Risk Factors
Viremia* / diagnosis,  virology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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