Document Detail

Use of Buprenorphine in Children With Chronic Pseudoobstruction Syndrome: Case Series and Review of Literature.
MedLine Citation:
PMID:  22688601     Owner:  NLM     Status:  Publisher    
OBJECTIVES:: Abdominal pain is the most challenging symptom in chronic intestinal pseudoobstruction (CIPO) syndrome, because of its severity and the limited availability of suitable opioid formulations, especially in pediatric patients with digestive problems. Most of the children with CIPO cannot tolerate oral formulations. CASE REPORTS:: We present 4 cases of children with CIPO and severe intractable abdominal pain, and report on the use of a recently available form of opioid, transdermal buprenorphine in a dosage of 5 mcg/h. DISCUSSION:: CIPO and the unique pharmacological profile of buprenorphine are reviewed briefly.
Sunisa Prapaitrakool; Markus W Hollmann; Hans Christian Wartenberg; Benedikt Preckel; Stefan Brugger
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-6-7
Journal Detail:
Title:  The Clinical journal of pain     Volume:  -     ISSN:  1536-5409     ISO Abbreviation:  -     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-6-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8507389     Medline TA:  Clin J Pain     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Anesthesiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
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