Document Detail

Use of Anorganic Bovine-Derived Hydroxyapatite Matrix (ABM)/Cell-Binding Peptide (P-15) in the Treatment of Isolated Class I Gingival Recession Defects: A Pilot Study.
MedLine Citation:
PMID:  21080787     Owner:  NLM     Status:  Publisher    
Background: This study evaluated clinically the treatment outcome of coronally positioned flap (CPF) associated with ABM/P-15 in terms of root coverage and gain in clinical attachment level (CAL) and bone height (BH) in isolated class I Gingival Recession Defects (GR). Methods: Fifteen healthy subjects with bilateral and comparable Miller class I GR were selected. The defects were randomly assigned either to the test group (CPF associated with ABM/P-15) or to the control group (CPF). Results: Six months after the surgery, a reduction in the GR was observed in the test and control groups (2.20±0.54 and 2.40±0.80 mm, respectively; p<0.001); with no intergroup difference (p=0.33). Complete root coverage was obtained in 10 and 11 defects in the test and control group, respectively. In the test group 85.56±21.69% and in the control group 90.00±18.42% of the exposed root was covered. Although not clinically significant, a statistically greater increase in the gingival thickness (GT) was observed in the test group (0.03 mm, p=0.01). CAL gain was significant in both groups (test group: 1.93±0.44mm; control group: 2.13±1.15 mm, p<0.001), with no inter-group difference (p=0.42). Inter- and intragroup differences in width of keratinized tissue and BH were not significant (p≥0.16). In the test group, a positive correlation was observed between BH at baseline and the reduction in GR (r= 0.56; p=0.03). Conclusion: In isolated class I GR, CPF associated with ABM/P-15 provided no significant difference in root coverage and CAL gain when compared to CPF alone. In the ABM/P-15 group, a greater reduction in GR was associated with higher bone level at baseline.
Carlos A Nazareth; Patricia R Cury
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2010-11-16
Journal Detail:
Title:  Journal of periodontology     Volume:  -     ISSN:  1943-3670     ISO Abbreviation:  J. Periodontol.     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-11-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8000345     Medline TA:  J Periodontol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Private Practice, Betim, Minas Gerais, Brazil.
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