| Use of Anorganic Bovine-Derived Hydroxyapatite Matrix (ABM)/Cell-Binding Peptide (P-15) in the Treatment of Isolated Class I Gingival Recession Defects: A Pilot Study. | |
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MedLine Citation:
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PMID: 21080787 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Background: This study evaluated clinically the treatment outcome of coronally positioned flap (CPF) associated with ABM/P-15 in terms of root coverage and gain in clinical attachment level (CAL) and bone height (BH) in isolated class I Gingival Recession Defects (GR). Methods: Fifteen healthy subjects with bilateral and comparable Miller class I GR were selected. The defects were randomly assigned either to the test group (CPF associated with ABM/P-15) or to the control group (CPF). Results: Six months after the surgery, a reduction in the GR was observed in the test and control groups (2.20±0.54 and 2.40±0.80 mm, respectively; p<0.001); with no intergroup difference (p=0.33). Complete root coverage was obtained in 10 and 11 defects in the test and control group, respectively. In the test group 85.56±21.69% and in the control group 90.00±18.42% of the exposed root was covered. Although not clinically significant, a statistically greater increase in the gingival thickness (GT) was observed in the test group (0.03 mm, p=0.01). CAL gain was significant in both groups (test group: 1.93±0.44mm; control group: 2.13±1.15 mm, p<0.001), with no inter-group difference (p=0.42). Inter- and intragroup differences in width of keratinized tissue and BH were not significant (p≥0.16). In the test group, a positive correlation was observed between BH at baseline and the reduction in GR (r= 0.56; p=0.03). Conclusion: In isolated class I GR, CPF associated with ABM/P-15 provided no significant difference in root coverage and CAL gain when compared to CPF alone. In the ABM/P-15 group, a greater reduction in GR was associated with higher bone level at baseline. |
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Authors:
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Carlos A Nazareth; Patricia R Cury |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2010-11-16 |
Journal Detail:
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Title: Journal of periodontology Volume: - ISSN: 1943-3670 ISO Abbreviation: J. Periodontol. Publication Date: 2010 Nov |
Date Detail:
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Created Date: 2010-11-17 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8000345 Medline TA: J Periodontol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Private Practice, Betim, Minas Gerais, Brazil. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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