Document Detail


Urticaria: selected highlights and recent advances.
MedLine Citation:
PMID:  16310530     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Urticaria has been called a vexing problem and remains so today. The most important part of the diagnostic evaluation remains a comprehensive and detailed history and physical examination, supplemented with limited laboratory testing. Although acute urticaria has been relatively well understood for some time, significant and important recent advances in under-standing the pathogenesis of chronic urticaria are beginning to provide insight in this challenging field, notably the identification of many of these patients with an autoimmune etiology. Antihistamines of various types continue to represent the keystone of symptomatic treatment, with adjunctive support from medications of other classes, such as antileukotrienes, adrenergics, and immunosuppressive and anti-inflammatory agents (including steroids and cyclosporine). Although some progress has been made at improving symptomatic control of urticaria, further research and discovery are necessary before there can yet be an effective impact on the underlying course and natural history of this condition.
Authors:
Donald A Dibbern
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The Medical clinics of North America     Volume:  90     ISSN:  0025-7125     ISO Abbreviation:  Med. Clin. North Am.     Publication Date:  2006 Jan 
Date Detail:
Created Date:  2005-11-28     Completed Date:  2006-02-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2985236R     Medline TA:  Med Clin North Am     Country:  United States    
Other Details:
Languages:  eng     Pagination:  187-209     Citation Subset:  AIM; IM    
Affiliation:
Division of Allergy and Clinical Immunology, Oregon Health and Sciences University, Portland, OR 97239-3098, USA. dibbernd@ohsu.edu
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MeSH Terms
Descriptor/Qualifier:
Acute Disease
Chronic Disease
Humans
Prognosis
Urticaria / diagnosis*,  etiology*,  therapy

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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