Document Detail

Urologic anomalies and two-vessel umbilical cords: what are the implications?
MedLine Citation:
PMID:  12648433     Owner:  NLM     Status:  MEDLINE    
A two-vessel umbilical cord (or single umbilical artery) is a perinatal finding that may be detected in infants with congenital or chromosomal abnormalities. Its presence has been associated with an increased risk of genitourinary defects. The urologic anomalies that typically are associated with a two-vessel cord often are minor and self-limiting. These defects usually can be detected perinatally in routine prenatal screening ultrasonographic examinations. The neonatal physical examination, an additional postnatal ultrasonography, and possibly a voiding cystourethrogram will be sufficient to complete the screening for genitourinary abnormalities in children with a single umbilical artery. Infants with two-vessel umbilical cords do not require additional screening for genitourinary defects, unless the imaging or amniocentesis detects a genitourinary abnormality. This review details the history of two-vessel cords and the associated genitourinary anomalies.
Christopher W Johnson; Steven Y Tennenbaum
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current urology reports     Volume:  4     ISSN:  1527-2737     ISO Abbreviation:  Curr Urol Rep     Publication Date:  2003 Apr 
Date Detail:
Created Date:  2003-03-21     Completed Date:  2003-06-11     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  100900943     Medline TA:  Curr Urol Rep     Country:  United States    
Other Details:
Languages:  eng     Pagination:  146-50     Citation Subset:  IM    
Department of Urology, Columbia University, New York Presbyterian Hospital, Irving Pavilion, 11th Floor, 161 Fort Washington Avenue, New York, NY 10032, USA.
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MeSH Terms
Fetal Diseases / diagnosis
Prenatal Diagnosis
Umbilical Cord / abnormalities*,  blood supply
Urogenital Abnormalities / complications*,  diagnosis

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