Document Detail

Urine metabolite values in fed and nonfed clinically normal beagles.
MedLine Citation:
PMID:  1767974     Owner:  NLM     Status:  MEDLINE    
Twenty-four-hour excretion of urine metabolites was determined in 33 clinically normal Beagles during periods of consumption of a standard diet and when food was withheld. The goal was to determine normal canine values for urine analytes incriminated in the genesis of calcium oxalate uroliths. During periods when dogs consumed food, dairy urinary excretion of calcium, uric acid, sodium, potassium, magnesium, ammonium, and hydrogen ions were significantly (P = 0.0004, 0.0038, 0.001, 0.0001, 0.0004, 0.0001, and 0.024, respectively) higher than when food was withheld. Urinary excretion of phosphorus, oxalate, and citrate were not significantly different between samples obtained during periods of food consumption and when food was withheld. Male dogs excreted significantly higher quantities of urine oxalate than females during fed (P = 0.003) and nonfed (P = 0.003) conditions. When food was withheld, urinary uric acid excretion was significantly higher in males than females (P = 0.01). Females excreted significantly more urine calcium than males when food was withheld (P = 0.003). Our results indicated that dietary conditions influence the quantity of sodium, potassium, calcium, magnesium, and uric acid excreted in the urine of clinically normal dogs; therefore, dietary conditions should be considered when measuring the concentration of these analytes in urine.
J P Lulich; C A Osborne; D J Polzin; S D Johnston; M L Parker
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  American journal of veterinary research     Volume:  52     ISSN:  0002-9645     ISO Abbreviation:  Am. J. Vet. Res.     Publication Date:  1991 Oct 
Date Detail:
Created Date:  1992-02-14     Completed Date:  1992-02-14     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0375011     Medline TA:  Am J Vet Res     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1573-8     Citation Subset:  IM    
Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St Paul 55108.
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MeSH Terms
Ammonia / urine
Animal Feed*
Calcium / blood,  urine
Citrates / urine
Dogs / urine*
Eating / physiology*
Electrolytes / blood,  urine
Oxalates / urine
Parathyroid Hormone / blood
Sex Characteristics
Uric Acid / urine
Reg. No./Substance:
0/Citrates; 0/Electrolytes; 0/Oxalates; 0/Parathyroid Hormone; 69-93-2/Uric Acid; 7440-70-2/Calcium; 7664-41-7/Ammonia

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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