Document Detail


Urine ketone dip test as a screen for ketonemia in diabetic ketoacidosis and ketosis in the emergency department.
MedLine Citation:
PMID:  9174517     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
STUDY OBJECTIVE: To determine the sensitivity of the urine ketone dip test (UKDT) for the detection of ketonemia in patients with diabetic ketoacidosis (DKA) and diabetic ketosis (DK) in the ED. METHODS: We conducted a retrospective chart review in the ED of an urban, university-affiliated county teaching hospital. The study population comprised patients seen in the ED during 1994 and 1995 with a discharge diagnosis of DKA or DK and underwent urinalysis within 4 hours of the initial serum electrolyte and ketone determinations. We calculated test sensitivity, along with 95% confidence intervals (CIs). RESULTS: One hundred forty-eight patients with 223 occurrences diagnosed as DKA or DK were seen in the ED during the study period. One hundred fourteen patients with 146 occurrences of DKA or DK met all inclusion criteria; these patients made up the study group. There were 99 cases of DKA and 47 cases of DK. The sensitivity of the UKDT for the detection of ketonemia in all patients with DKA or DK was 97% (95% CI, 94% to 99%). In the subgroup of patients with DKA, the sensitivity of the UK was 97% (95% CI, 92% to 99%). For patients with DK, the sensitivity of the UK was 98% (95% CI, 89% to 99%). CONCLUSION: The UKDT is highly sensitive for the presence of serum ketones in patients with DKA and DK. Prospective study is suggested to determine the specificity of the UKDT in this application and to validate its use as a screening tool for the detection of ketonemia in DKA and DK.
Authors:
G W Hendey; T Schwab; T Soliz
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Annals of emergency medicine     Volume:  29     ISSN:  0196-0644     ISO Abbreviation:  Ann Emerg Med     Publication Date:  1997 Jun 
Date Detail:
Created Date:  1997-07-11     Completed Date:  1997-07-11     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8002646     Medline TA:  Ann Emerg Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  735-8     Citation Subset:  AIM; IM    
Affiliation:
Department of Emergency Medicine, University Medical Center, Fresno, CA, USA.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Aged, 80 and over
Diabetic Ketoacidosis / diagnosis*,  urine*
Emergency Service, Hospital
Humans
Ketones / urine*
Ketosis / diagnosis*,  urine*
Mass Screening / methods*
Middle Aged
Reagent Strips / diagnostic use*
Reproducibility of Results
Retrospective Studies
Sensitivity and Specificity
Chemical
Reg. No./Substance:
0/Ketones; 0/Reagent Strips

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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