| Urine albumin excretion, within normal range, reflects increasing prevalence of metabolic syndrome in patients with essential hypertension. | |
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MedLine Citation:
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PMID: 20695936 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Microalbuminuria is a prognostic marker of cardiovascular disease and is related to metabolic syndrome (MetS). For this purpose, the authors examined the relationship of low grade albuminuria to MetS, using 4 current definitions and a MetS score. They studied 6650 consecutive, nondiabetic, hypertensive patients with normal microalbumin excretion. MetS was defined by Adult Treatment Panel III, American Heart Association, World Heart Organization, International Diabetes Federation criteria, and MetS Gruppo Italiano per lo Studio della Streptochinasi nell'Infarcto Miocardico (GISSI) score. Urine microalbumin concentration was measured after a 24-hour urine collection by immunonephelometry. By all definitions, hypertensive patients with MetS had higher microalbumin levels. Significantly higher microalbumin levels were observed as the number of metabolic components rose. After adjustment for systolic blood pressure, the strength of this association was reduced to a nonsignificant level. Microalbumin levels, within normal range, are increased in patients with MetS, irrespective of the definition criteria. |
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Authors:
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Gregory Vyssoulis; Eva Karpanou; Pangiotis Spanos; Stella-Maria Kyvelou; Dionysios Adamopoulos; Christodoulos Stefanadis |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of clinical hypertension (Greenwich, Conn.) Volume: 12 ISSN: 1751-7176 ISO Abbreviation: J Clin Hypertens (Greenwich) Publication Date: 2010 Aug |
Date Detail:
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Created Date: 2010-08-10 Completed Date: 2010-12-16 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100888554 Medline TA: J Clin Hypertens (Greenwich) Country: United States |
Other Details:
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Languages: eng Pagination: 597-602 Citation Subset: IM |
Affiliation:
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Hypertension Unit, 1st Cardiology Clinic, Athens University, Hippokration Hospital, V. Sofias 108 Avenue, Athens, Greece. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Albuminuria / diagnosis*, urine* Cardiovascular Diseases / epidemiology Cohort Studies Female Humans Hypertension / complications*, urine Male Metabolic Syndrome X / epidemiology*, urine Middle Aged Prevalence Reference Values Retrospective Studies Risk Factors |
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