| Urinary tract infection in children with nephrotic syndrome in Kano, Nigeria. | |
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MedLine Citation:
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PMID: 19763005 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Nephrotic syndrome is a common childhood renal disorder; the prevalence of Urinary tract infection (UTI) in these patients is high. The increased prevalence of UTI are due to immunoglobulin loss, defective T cell function, presence of ascites and relative malnutrition. OBJECTIVE: The study is to evaluate the prevalence of UTI , its etiological agents, antibiotics, sensitivity pattern and the outcome in children with nephrotic syndrome. METHODS: A prospective study of all patients with diagnosis of nephrotic syndrome from January 2003 to December 2006. Urine specimen were routinely obtained by clean catch method following careful preparation urethral orifices. The specimens were processed immediately. Five millimeters (5 ml) loopful of the sample were inoculated on a blood agar and CLED agar plates. Identification of the organism to species level was by using stokes disc diffusion technique. RESULTS: Forty two patients were studied. The mean age and SEM for males was 8.2 + 0.5 years and females with 7.9 + 0.8 years. The age range was two to fifteen years UTI was caused predominantly by Staphylococcus aureus in 67.9%, Klebsiella species (17.9%) and Pseudomonas (14.2%). There was high in vitro resistance of these organisms to nalidixic acid and ampicillin but sensitive to cefotaxime, ceftriazone and ciprofloxacin. CONCLUSION: It is recommend that UTI should be sought for in patients with nephrotic syndrome and treatment should be prompt and appropriate. |
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Authors:
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S I Adeleke; M O Asani |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Annals of African medicine Volume: 8 ISSN: 0975-5764 ISO Abbreviation: Ann Afr Med Publication Date: 2009 Jan-Mar |
Date Detail:
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Created Date: 2009-09-18 Completed Date: 2010-05-26 Revised Date: 2010-09-21 |
Medline Journal Info:
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Nlm Unique ID: 101231417 Medline TA: Ann Afr Med Country: Nigeria |
Other Details:
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Languages: eng Pagination: 38-41 Citation Subset: IM |
Affiliation:
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Department of Paediatrics, Faculty of Medicine Bayero University, Kano, Nigeria. adelekesolo@yahoo.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Age Distribution Anti-Infective Agents, Urinary / therapeutic use* Child Child, Preschool Drug Resistance, Multiple, Bacterial Female Humans Klebsiella / drug effects, isolation & purification Male Microbial Sensitivity Tests Nephrotic Syndrome / complications*, epidemiology Nigeria / epidemiology Prevalence Prospective Studies Pseudomonas / drug effects, isolation & purification Sex Factors Staphylococcus aureus / drug effects, isolation & purification Treatment Outcome Urinary Tract Infections / drug therapy*, epidemiology, etiology* Urine / microbiology |
| Chemical | |
Reg. No./Substance:
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0/Anti-Infective Agents, Urinary |
| Comments/Corrections | |
Comment In:
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Ann Afr Med. 2010 Apr-Jun;9(2):105; author reply 105-6
[PMID:
20587934
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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