Document Detail

Urinary storage symptoms and comorbidities: a prospective population cohort study in middle-aged and older women.
MedLine Citation:
PMID:  16234314     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: to identify predictive morbidities for urinary storage syndromes including indicators for neurological, musculoskeletal, cardiovascular, immune, lower bowel and psychological systems. This is the first study to test prior hypotheses, based on a literature review. DESIGN: this was a prospective cohort study involving 12,570 female respondents aged 40 or more registered with general practitioners and living at home in Leicestershire. Postal questionnaires were used at baseline and 1-year follow-up (response rates 65 and 79%, respectively). MEASURES: pure stress urinary incontinence (SUI) and overactive bladder syndrome (OAB) were defined using standardised symptom indicators. Specific morbidities included reported medical diagnoses, standardised symptoms and general health indicators. Associations were identified using logistic regression, adjusting for age and physical impairment, with separate models for general and specific morbidities. RESULTS: multivariate morbidities consistently associated (i.e. both longitudinally and cross-sectionally) were SUI-cystitis and obesity; and OAB-bowel urgency, osteoporosis, imbalance, ankle swelling, cystitis, poor health and old age. Other independent predictors were SUI-multiple sclerosis and joint pain; and OAB-deep vein thrombosis and diabetes. Consistent univariate indicators supported neurological, musculoskeletal, cardiovascular, immunological and psychological connections with both types of storage disorder plus an association with lower bowel problems for OAB. CONCLUSIONS: abnormal urinary storage symptoms were predicted by obesity and poor general health, involving a range of systems of the body. OAB showed more extensive links than SUI with specific morbidities, including more medically diagnosed as opposed to symptom-based conditions. These findings were independent of problems with physical impairment.
Catherine W McGrother; Madeleine M K Donaldson; Tom Hayward; Ruth Matthews; Helen M Dallosso; Colin Hyde;
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Publication Detail:
Type:  Comparative Study; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't     Date:  2005-10-18
Journal Detail:
Title:  Age and ageing     Volume:  35     ISSN:  0002-0729     ISO Abbreviation:  Age Ageing     Publication Date:  2006 Jan 
Date Detail:
Created Date:  2005-12-20     Completed Date:  2006-04-18     Revised Date:  2009-06-26    
Medline Journal Info:
Nlm Unique ID:  0375655     Medline TA:  Age Ageing     Country:  England    
Other Details:
Languages:  eng     Pagination:  16-24     Citation Subset:  IM    
Department of Epidemiology and Public Health, University of Leicester, 22-28 Princess Road West, Leicester LE1 6TP, UK.
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MeSH Terms
Aged, 80 and over
Cardiovascular Diseases / epidemiology
Cross-Sectional Studies
Follow-Up Studies
Middle Aged
Neuromuscular Diseases / epidemiology
Obesity / epidemiology
Odds Ratio
Prospective Studies
Risk Factors
Urinary Incontinence / epidemiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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