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Urinary sludge caused by ceftriaxone in a young boy.
MedLine Citation:
PMID:  22690306     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
It is known that ceftriaxone administration is associated with biliary pseudolithiasis, although the development of urolithiasis has been rarely reported. We encountered a young male with bacterial meningitis complicated by urinary precipitates composed of ceftriaxone-calcium salt which is confirmed by high-performance liquid chromatography. This patient suggested that ceftriaxone significantly increased urinary excretion of calcium, which may be linked to ceftriaxone-related urolithiasis or sludge. It is therefore worthwhile to monitor the levels of urinary calcium to creatinine ratio in patients on ceftriaxone, as they may be at greater risk for developing large stones and renal damage.
Authors:
Takahisa Kimata; Kazunari Kaneko; Masaya Takahashi; Sohsaku Yamanouchi; Shoji Tsuji; Minoru Kino
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Publication Detail:
Type:  Journal Article     Date:  2012-03-26
Journal Detail:
Title:  Pediatric reports     Volume:  4     ISSN:  2036-7503     ISO Abbreviation:  Pediatr Rep     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2012-06-12     Completed Date:  2012-08-23     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  101551542     Medline TA:  Pediatr Rep     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  e14     Citation Subset:  -    
Affiliation:
Department of Pediatrics, Kansai Medical University.
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