Document Detail


Urinary prostacyclin and thromboxane A2 metabolites in preterm and full-term infants in relation to plasma renin activity and blood pressure.
MedLine Citation:
PMID:  6753956     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The metabolites of prostacyclin and thromboxane A2, 6-ketoprostaglandin F1 alpha and thromboxane B2, were measured in urine of 27 preterm and 21 full-term infants. Their values were analyzed in correlation to plasma renin activity, urinary function, and systolic blood pressure. The 6-ketoprostaglandin F1 alpha excretion was significantly higher in the preterm infants as compared to the full-term infants (p less than 0.001). This decrease of 6-ketoprostaglandin F1 alpha in the full-term infants was associated with a decrease in the plasma renin activity and an increase in systolic blood pressure. In contrast, the urinary excretion of thromboxane B2 was low, without significant difference between the two groups, and there was no correlation to the parameters mentioned above.
Authors:
R Joppich; I Häuser
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Biology of the neonate     Volume:  42     ISSN:  0006-3126     ISO Abbreviation:  Biol. Neonate     Publication Date:  1982  
Date Detail:
Created Date:  1983-01-19     Completed Date:  1983-01-19     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0247551     Medline TA:  Biol Neonate     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  179-84     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Blood Pressure
Epoprostenol / urine*
Female
Humans
Infant, Newborn*
Infant, Premature*
Male
Osmolar Concentration
Potassium / urine
Prostaglandins / urine*
Prostaglandins F / urine
Renin / blood
Sodium / urine
Thromboxane A2 / urine*
Thromboxanes / urine*
Chemical
Reg. No./Substance:
0/Prostaglandins; 0/Prostaglandins F; 0/Thromboxanes; 35121-78-9/Epoprostenol; 57576-52-0/Thromboxane A2; 7440-09-7/Potassium; 7440-23-5/Sodium; 745-62-0/prostaglandin F1; EC 3.4.23.15/Renin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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