| Urinary pregnanetriol excretion in hirsutism. | |
| | |
MedLine Citation:
|
PMID: 199379 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Eighteen consecutive hirsute women attending an endocrine clinic have been studied by measurement of the urinary pregnanetriol excretion before and following the concurrent administration of corticotrophin and metyrapone. An abnormal increment in pregnanetriol excretion was observed in 11 of these 18 patients. It is suggested that this is evidence that an adrenal abnormality, probably operative at the 21-hydroxylase level, might be a factor responsible for the hirsutism in these 11 patients. Five adrenalectomized women who were also studied showed no significant increase in urinary pregnanetriol excretion in response to concurrent corticotrophin and metyrapone administration. |
| | |
Authors:
|
W Van't Hoff; E J Bicknell; P M Horrocks; J A Fleetwood; M Inthuprapa; R Hall |
Related Documents
:
|
9406009 - The effect of dietary enrichment with fish-oil on urinary excretion of n-acetyl-beta-d-... 8716209 - The effects of platinum chemotherapy on essential trace elements. 15607359 - Successful treatment of systemic mastocytosis with high-dose interferon-alfa: long-term... 12495779 - Hormonal changes during 17 days of head-down bed-rest. 8287549 - Radioimmunoassay of 2-hydroxyestrone in urine. 6668759 - Sulbenicillin-induced kaliuresis in man. 22541999 - Male acquired hypogonadotropic hypogonadism: diagnosis and treatment. 8698859 - Role of cortisol in the pathogenesis of deficient counterregulation after antecedent hy... 8200929 - Alterations in growth hormone secretion and clearance in peripubertal boys with chronic... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Clinica chimica acta; international journal of clinical chemistry Volume: 80 ISSN: 0009-8981 ISO Abbreviation: Clin. Chim. Acta Publication Date: 1977 Oct |
Date Detail:
|
Created Date: 1977-12-29 Completed Date: 1977-12-29 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 1302422 Medline TA: Clin Chim Acta Country: NETHERLANDS |
Other Details:
|
Languages: eng Pagination: 373-9 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adrenalectomy Adrenocorticotropic Hormone / diagnostic use Adult Female Hirsutism / urine* Humans Metyrapone / diagnostic use Middle Aged Pregnanetriol / urine* Time Factors |
| Chemical | |
Reg. No./Substance:
|
27178-64-9/Pregnanetriol; 54-36-4/Metyrapone; 9002-60-2/Adrenocorticotropic Hormone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: The effect of temperature on the kinetic constants of human lactate dehydrogenase 1 and 5.
Next Document: How to collect blood for the measurement of HGH, LH, FSH, cyclic AMP, folic acid, cortisol and testo...