Document Detail

Urinary liver fatty acid-binding protein: another novel biomarker of acute kidney injury.
MedLine Citation:
PMID:  20354549     Owner:  NLM     Status:  MEDLINE    
Liver fatty acid-binding protein (L-FABP) binds selectively to intracellular free unsaturated fatty acids and lipid peroxidation products during hypoxic tissue injury. Urinary L-FABP is a potential biomarker for the detection and assessment of acute kidney injury (AKI). Ferguson et al. have demonstrated in a cross-sectional study that urinary L-FABP is an excellent biomarker of AKI and may be useful in predicting dialysis-free survival. This study did not assess utility for early diagnosis of AKI.
Blaithin A McMahon; Patrick Thomas Murray
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Kidney international     Volume:  77     ISSN:  1523-1755     ISO Abbreviation:  Kidney Int.     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-03-31     Completed Date:  2010-06-29     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0323470     Medline TA:  Kidney Int     Country:  United States    
Other Details:
Languages:  eng     Pagination:  657-9     Citation Subset:  IM    
University College Dublin, Catherine McAuley Centre, Dublin, Ireland.
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MeSH Terms
Biological Markers / metabolism
Early Diagnosis
Fatty Acid-Binding Proteins / metabolism*
Fatty Acids, Nonesterified / metabolism
Fatty Acids, Unsaturated / metabolism
Kidney / metabolism*
Kidney Failure, Acute / metabolism*
Lipid Peroxidation
Urinary Tract / metabolism*
Reg. No./Substance:
0/Biological Markers; 0/Fatty Acid-Binding Proteins; 0/Fatty Acids, Nonesterified; 0/Fatty Acids, Unsaturated

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