| Urinary incontinence should be added to the manifestation in women with Marfan syndrome. | |
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MedLine Citation:
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PMID: 20066398 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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INTRODUCTION AND HYPOTHESIS: We aimed to compare the incidence of urinary incontinence in women with Marfan syndrome and controls, hypothesizing that connective tissue abnormality could contribute to urinary incontinence. METHODS: A cross-sectional historical cohort study was conducted on 14 premenopausal women with Marfan syndrome and 534 controls using Urogenital Distress Inventory Short Form and Incontinence Impact Questionnaire Short Form. RESULTS: Marfan subjects had significantly higher incidence of urinary symptoms, stress urinary incontinence (SUI) and urge urinary incontinence (UUI) than controls (P = 0.02, P = 0.03, P = 0.02), despite their lower parity (P = 0.01). Direct logistic regression analysis indicated that Marfan syndrome, parity and age were associated with SUI; while Marfan syndrome was the only significant predictor of UUI. CONCLUSIONS: Premenopausal women with Marfan syndrome had a higher incidence of reported urinary symptoms. Urinary incontinence should be added to the list of clinical manifestations in women with Marfan syndrome. |
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Authors:
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Symphorosa S C Chan; David K H Chan; Selina M W Pang; Stephen T S Lam; Terence T H Lao; Kwong-Wai Choy |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-01-12 |
Journal Detail:
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Title: International urogynecology journal Volume: 21 ISSN: 1433-3023 ISO Abbreviation: Int Urogynecol J Publication Date: 2010 May |
Date Detail:
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Created Date: 2010-03-26 Completed Date: 2010-07-15 Revised Date: 2011-08-18 |
Medline Journal Info:
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Nlm Unique ID: 101567041 Medline TA: Int Urogynecol J Country: England |
Other Details:
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Languages: eng Pagination: 583-7 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, NT Hong Kong, SAR, China. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Cross-Sectional Studies Female Humans Marfan Syndrome / complications* Urinary Incontinence / epidemiology*, etiology* |
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