Document Detail

Urinary fluoride excretion by preschool children in six European countries.
MedLine Citation:
PMID:  15016119     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To measure and compare 24-h urinary fluoride excretion in children aged 1.5-3.5 years from European study sites and to use these data to estimate the 24-h fluoride intake. METHOD: Twenty-four-hour urine samples were collected from 3-year-old children (n = 86) who were already participating in a European multicentre study. Samples were collected from Cork, Ireland (n = 19) where the water is fluoridated to a concentration between 0.8 and 1.0 ppm and from five sites with a water fluoride concentration <0.15 ppm: Knowsley, England (n = 18); Oulu, Finland (n = 18); Reykjavik, Iceland (n = 4); Haarlem, the Netherlands (n = 6); Almada/Setubal, Portugal (n = 21). The volume of the samples was measured; they were analysed for fluoride concentration and the 24-h urinary fluoride excretion was calculated. From this an estimate of the daily fluoride intake was made. RESULTS: It was found that the mean fluoride excretion in response to the usual conditions of fluoride intake in the children in the nonfluoridated areas ranged from 0.16 mg (+/-0.08) in Oulu to 0.33 mg (+/-0.27) in Almada/Setubal with an overall mean of 0.23 mg (+/-0.19). The mean 24-h fluoride excretion in fluoridated Cork was 0.37 mg (+/-0.11). There was a significant difference between the fluoride excretion in the nonfluoridated areas and that in the fluoridated areas, and the data were broadly in agreement with WHO standards. CONCLUSIONS: The daily urinary fluoride excretion and estimated fluoride intake in these children appeared to be within acceptable limits.
Clare E Ketley; Judith A Cochran; W Peter Holbrook; Leonor Sanches; Cor van Loveren; Anna-Maria Oila; Denis M O'Mullane
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Community dentistry and oral epidemiology     Volume:  32 Suppl 1     ISSN:  0301-5661     ISO Abbreviation:  Community Dent Oral Epidemiol     Publication Date:  2004 Apr 
Date Detail:
Created Date:  2004-03-12     Completed Date:  2004-04-27     Revised Date:  2009-01-29    
Medline Journal Info:
Nlm Unique ID:  0410263     Medline TA:  Community Dent Oral Epidemiol     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  62-8     Citation Subset:  D; IM    
Department of Clinical Dental Sciences, The University of Liverpool, Liverpool, UK.
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MeSH Terms
Cariostatic Agents / administration & dosage*
Child, Preschool
Fluorides / administration & dosage*,  urine*
Reg. No./Substance:
0/Cariostatic Agents; 0/Fluorides

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