Document Detail

Urinary excretion of glomerular basement membrane antigens in premature infants and the newborn.
MedLine Citation:
PMID:  526493     Owner:  NLM     Status:  MEDLINE    
25 premature infants, 8 mature newborns and 25 children between 5 and 15 years of age were examined for urinary excretion of glomerular basement membrane (GBM) antigens. For the characterization of the excreted GBM antigen, immunoelectrophoresis was applied. In the group of 25 premature infants 23 showed alpha-1-mobility, in the group of 8 mature newborns all showed alpha-1-mobility, and in the group of the 25 children aged 5--15 years 24 showed migration into the alpha-2-zone. Differentiating, whether the difference between the immature and mature GBM is quantitative or qualitative, the immunoelectrophoretical difference points to the interpretation that the premature GMB shows a unique chemical composition.
G Lubec; H Coradello
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Biology of the neonate     Volume:  36     ISSN:  0006-3126     ISO Abbreviation:  Biol. Neonate     Publication Date:  1979  
Date Detail:
Created Date:  1980-04-17     Completed Date:  1980-04-17     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0247551     Medline TA:  Biol Neonate     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  277-81     Citation Subset:  IM    
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MeSH Terms
Age Factors
Antigens / urine*
Basement Membrane / immunology*
Child, Preschool
Immunization Schedule
Infant, Newborn*
Infant, Premature*
Kidney Glomerulus / immunology*
Reg. No./Substance:

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