Document Detail


Urinary erythrocyte morphology as a diagnostic aid in haematuria.
MedLine Citation:
PMID:  8153706     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The value of urinary erythrocyte morphology in diagnosing glomerular and nonglomerular haematuria was studied using phase contrast microscopy in 105 patients with significant haematuria. Fifty-eight (93.6%) out of 62 patients with glomerulonephritis had dysmorphic erythrocytes and 40 (93.1%) out of the 43 patients with nonglomerular disease had isomorphic erythrocytes in the urine. A mixed picture of glomerular and nonglomerular haematuria was seen in 5 patients. The sensitivity was 93.6%, the specificity was 97.7% and the positive predictive value was 98.3% for glomerulonephritis in patients with dysmorphic haematuria. The positive predictive value for a nonglomerular source of bleeding was 96.7% with isomorphic haematuria. It is concluded that phase contrast microscopic examination of erythrocytes in urine is a simple, inexpensive and noninvasive technique that reliably distinguishes between glomerular and nonglomerular bleeding in patients.
Authors:
G Ahmad; M Segasothy; Z Morad
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Singapore medical journal     Volume:  34     ISSN:  0037-5675     ISO Abbreviation:  Singapore Med J     Publication Date:  1993 Dec 
Date Detail:
Created Date:  1994-05-12     Completed Date:  1994-05-12     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0404516     Medline TA:  Singapore Med J     Country:  SINGAPORE    
Other Details:
Languages:  eng     Pagination:  486-8     Citation Subset:  IM    
Affiliation:
Department of Nephrology, General Hospital Kuala Lumpur, Malaysia.
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MeSH Terms
Descriptor/Qualifier:
Erythrocyte Count
Erythrocytes / pathology*
Erythrocytes, Abnormal / pathology
Glomerulonephritis / diagnosis,  urine
Hematuria / diagnosis*,  etiology,  urine*
Hemoglobins / analysis
Humans
Kidney Calculi / diagnosis,  urine
Microscopy, Phase-Contrast
Single-Blind Method
Chemical
Reg. No./Substance:
0/Hemoglobins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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