Document Detail


Urinary dysfunction in multiple sclerosis.
MedLine Citation:
PMID:  19560927     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We aimed to determine the prevalence of urinary symptoms and complications in multiple sclerosis (MS) and to investigate the correlation of these symptoms and complications with urodynamic findings and disease characteristics (primary progressive, relapsing-remitting and secondary progressive). Fifty-two patients with MS were enrolled in the study. Patients were divided into three clinical types: primary progressive, relapsing-remitting and secondary progressive. Urological symptoms and complications were recorded. Each patient underwent a urodynamic investigation. Patients were evaluated for overall disability using the Expanded Disability Status Scale (EDSS). We found that 22 patients had primary progressive, 18 patients had relapsing-remitting and 12 patients had secondary progressive MS. Urgency was the most frequent urinary symptom (65%). Urinary infection was the most frequent urinary complication (15%). Detrusor hyperreflexia was found to be the main bladder dysfunction (27%). Detrusor sphincter dyssynergia was found in 25% of patients, and detrusor hyporeflexia was detected in 6%. No relationship was found between urinary symptoms and urodynamic abnormalities (p>0.05) and between urinary complications and urodynamic findings (p>0.05). No significant correlation was found between disease characteristics and urinary symptoms, urinary complications or urodynamic findings (p>0.05). We suggest that the assessment of urological symptoms and urodynamic evaluation is critical for evaluating quality of life in MS.
Authors:
G F Nakipoglu; A Z Kaya; G Orhan; O Tezen; H Tunc; N Ozgirgin; F Ak
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Publication Detail:
Type:  Journal Article     Date:  2009-06-27
Journal Detail:
Title:  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia     Volume:  16     ISSN:  0967-5868     ISO Abbreviation:  -     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2009-08-26     Completed Date:  2009-10-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9433352     Medline TA:  J Clin Neurosci     Country:  Scotland    
Other Details:
Languages:  eng     Pagination:  1321-4     Citation Subset:  IM    
Affiliation:
Ankara Physical Medicine and Rehabilitation Education and Research Hospital, 5th Physical Medicine and Rehabilitation Clinic, Turkey. g_nakipoglu@yahoo.com
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MeSH Terms
Descriptor/Qualifier:
Adult
Catheterization / methods
Cholinergic Antagonists / therapeutic use
Disease Progression
Female
Humans
Male
Middle Aged
Multiple Sclerosis / complications*
Retrospective Studies
Urination Disorders / drug therapy,  etiology*,  therapy
Young Adult
Chemical
Reg. No./Substance:
0/Cholinergic Antagonists

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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