Document Detail

Urinary cortisol and muscle mass in Turkana men.
MedLine Citation:
PMID:  15981185     Owner:  NLM     Status:  MEDLINE    
To determine the role of cortisol in modulating the effects of energetics on muscle mass in a subsistence society, measures of cortisol and body composition were obtained from a sample of Turkana men. Subjects were 63 settled and 69 nomadic men, ages 24 and older. Urinary cortisol was determined along with measures of muscle mass. Cortisol/creatinine ratio was higher among nomadic men (57.8 +/- 56.8 vs. 34.5 +/- 44.6; P < 0.001). Controlled for age, urinary cortisol was inversely related to arm muscle plus bone area (MPBA) among the nomadic (beta = -0.28; P = 0.04), but not the settled (beta = -0.04; P = 0.78) sample. Urinary cortisol was not related to any other measures of body composition. These results suggest that even in chronically undernourished populations, cortisol may be elevated primarily under conditions of acute nutritional stress. However, the catabolic effects of cortisol on muscle in our results may be confounded by other energetic factors, including energy availability.
William D Lukas; Benjamin C Campbell; Kenneth L Campbell
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  American journal of human biology : the official journal of the Human Biology Council     Volume:  17     ISSN:  1042-0533     ISO Abbreviation:  Am. J. Hum. Biol.     Publication Date:    2005 Jul-Aug
Date Detail:
Created Date:  2005-06-30     Completed Date:  2005-10-13     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8915029     Medline TA:  Am J Hum Biol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  489-95     Citation Subset:  IM    
Copyright Information:
Copyright 2005 Wiley-Liss, Inc
Department of Anthropology, Boston University, Massachusetts 02215, USA.
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MeSH Terms
Age Distribution
Aged, 80 and over
Biological Markers / urine
Body Composition / physiology*
Creatinine / urine
Hydrocortisone / urine*
Middle Aged
Muscle, Skeletal / physiology*
Reference Values
Retrospective Studies
Reg. No./Substance:
0/Biological Markers; 50-23-7/Hydrocortisone; 60-27-5/Creatinine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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