| Urinary catecholamine levels in the newborn infant. | |
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MedLine Citation:
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PMID: 3987707 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The urinary concentrations of dopamine, noradrenaline and adrenaline were measured by a radioenzymatic method in 212 full-term and premature newborns. The ranges, means and standard deviations from birth to 4 days + are presented. The excretion of dopamine was ten times that of noradrenaline or adrenaline. The absolute concentrations of each catecholamine were reduced as birth weight decreased. The values were increased in babies with fetal distress. Any changes found in hypoglycaemic or jaundiced infants were attributable to prematurity. Very high levels were found in a few infants given tolazoline. We speculate that the role of dopamine production and excretion in the newborn has been underestimated. Dopamine may have an important role to play in the homeostatic mechanisms of the newborn. |
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Authors:
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G M Maxwell; S Crompton; A Davies |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: European journal of pediatrics Volume: 143 ISSN: 0340-6199 ISO Abbreviation: Eur. J. Pediatr. Publication Date: 1985 Jan |
Date Detail:
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Created Date: 1985-06-12 Completed Date: 1985-06-12 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7603873 Medline TA: Eur J Pediatr Country: GERMANY, WEST |
Other Details:
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Languages: eng Pagination: 171-4 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Catecholamines
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urine* Creatinine / urine Dopamine / urine Epinephrine / urine Female Fetal Distress / urine Gestational Age Humans Hyaline Membrane Disease / urine Hypoglycemia / urine Infant, Newborn* Jaundice, Neonatal / urine Male Norepinephrine / urine Pregnancy Respiratory Distress Syndrome, Newborn / urine |
| Chemical | |
Reg. No./Substance:
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0/Catecholamines; 51-41-2/Norepinephrine; 51-43-4/Epinephrine; 60-27-5/Creatinine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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