Document Detail

Urinary catecholamine levels in the newborn infant.
MedLine Citation:
PMID:  3987707     Owner:  NLM     Status:  MEDLINE    
The urinary concentrations of dopamine, noradrenaline and adrenaline were measured by a radioenzymatic method in 212 full-term and premature newborns. The ranges, means and standard deviations from birth to 4 days + are presented. The excretion of dopamine was ten times that of noradrenaline or adrenaline. The absolute concentrations of each catecholamine were reduced as birth weight decreased. The values were increased in babies with fetal distress. Any changes found in hypoglycaemic or jaundiced infants were attributable to prematurity. Very high levels were found in a few infants given tolazoline. We speculate that the role of dopamine production and excretion in the newborn has been underestimated. Dopamine may have an important role to play in the homeostatic mechanisms of the newborn.
G M Maxwell; S Crompton; A Davies
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  European journal of pediatrics     Volume:  143     ISSN:  0340-6199     ISO Abbreviation:  Eur. J. Pediatr.     Publication Date:  1985 Jan 
Date Detail:
Created Date:  1985-06-12     Completed Date:  1985-06-12     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7603873     Medline TA:  Eur J Pediatr     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  171-4     Citation Subset:  IM    
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MeSH Terms
Catecholamines / urine*
Creatinine / urine
Dopamine / urine
Epinephrine / urine
Fetal Distress / urine
Gestational Age
Hyaline Membrane Disease / urine
Hypoglycemia / urine
Infant, Newborn*
Jaundice, Neonatal / urine
Norepinephrine / urine
Respiratory Distress Syndrome, Newborn / urine
Reg. No./Substance:
0/Catecholamines; 51-41-2/Norepinephrine; 51-43-4/Epinephrine; 60-27-5/Creatinine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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