Document Detail

Urinary albumin excretion in patients with renovascular hypertension.
MedLine Citation:
PMID:  1308723     Owner:  NLM     Status:  MEDLINE    
Twenty-four hour urinary excretion of albumin (UEalb), IgG and beta-2 microglobulin was investigated at a 3 hour-interval in a control group (C) of healthy subjects, in 30 patients with renovascular hypertension (RVH), and in 16 patients with essential hypertension (EH). Mean UEalb in RVH was significantly higher than in C. A significant direct correlation was demonstrated between diastolic blood pressure and UEalb (p < 0.01). Microalbuminuria (MA) > or = 30 micrograms.min-1 was found in about 18% of RVH patients; it was higher than 16.7 micrograms.min-1 in approx. 31%. These results did not substantially differ from those obtained in patients with EH. The cause for increased UEalb in hypertensive patients may be functional, haemodynamic changes, or structural ones. In either case, MA indicates renal injury, and these patients should be given increased attention when monitoring their blood pressure and when selecting antihypertensive drugs.
M Růzicka; J Stríbrná; M Englis; V Lánská; J Skibová; J Peregrin
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cor et vasa     Volume:  34     ISSN:  0010-8650     ISO Abbreviation:  Cor Vasa     Publication Date:  1992  
Date Detail:
Created Date:  1993-10-12     Completed Date:  1993-10-12     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372614     Medline TA:  Cor Vasa     Country:  CZECHOSLOVAKIA    
Other Details:
Languages:  eng     Pagination:  314-21     Citation Subset:  IM    
Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
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MeSH Terms
Circadian Rhythm
Hypertension / urine
Hypertension, Renovascular / urine*
Immunoglobulin G / urine
Middle Aged
beta 2-Microglobulin / urine
Reg. No./Substance:
0/Immunoglobulin G; 0/beta 2-Microglobulin

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