Document Detail


Urinary albumin and beta 2-microglobulin excretion rates in patients with systemic lupus erythematosus.
MedLine Citation:
PMID:  6154968     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The daily urinary albumin and beta 2-microglobulin excretion rates were measured with sensitive radioimmunoassays in 14 patients with systemic lupus erythematosus (SLE). The duration of SLE ranged from 0.5 to 18 years, mean 10 years. The mean age was 37 years. All patients except 5 received prednisone, 5-20 mg/day. None of the patients had proteinuria as judged by the "Albustix" test, and all had normal serum creatinine. The daily urinary albumin and beta 2-microglobulin excretion rates were nearly the same as those previously found by us in 27 adult control subjects with a mean age of 44 years. Our study shows that SLE patients without clinical proteinuria have a completely normal renal glomerular and tubular protein handling, irrespective of the duration of the disease.
Authors:
H H Parving; S F Sørensen; C E Mogensen; P Helin
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Scandinavian journal of rheumatology     Volume:  9     ISSN:  0300-9742     ISO Abbreviation:  Scand. J. Rheumatol.     Publication Date:  1980  
Date Detail:
Created Date:  1980-07-26     Completed Date:  1980-07-26     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0321213     Medline TA:  Scand J Rheumatol     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  49-51     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Albuminuria*
Beta-Globulins / urine*
Creatinine / blood
Female
Humans
Lupus Erythematosus, Systemic / urine*
Male
Middle Aged
Proteinuria / diagnosis
Radioimmunoassay
beta 2-Microglobulin / urine*
Chemical
Reg. No./Substance:
0/Beta-Globulins; 0/beta 2-Microglobulin; 60-27-5/Creatinine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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