| Urgent termination of pregnancy in pre-eclampsia and panel of antiphospholipid antibodies. | |
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MedLine Citation:
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PMID: 19895376 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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PROBLEM: The present work was undertaken to investigate the occurence of autoantibodies to eight various phospholipids in time of urgent termination of the pregnancy (sectio caesarea) in patients in reproductive age with severe preeclamptic symptoms. METHOD OF STUDY: Autoantibodies against annexin V, ph-serine, ph-ethanolamine, ph-inositol, ph-DL-glycerol, cardiolipin, beta2-glycoprotein I (beta2-GPI), and phosphatidic acid were studied by ELISA methods. RESULTS: Increased levels of IgA-beta2-glycoprotein I, IgG-beta2-glycoprotein I, IgG- anti-ph-serine, and IgG-anticardiolipin were found in sera of preeclamptic women in the time of urgent sectio caesarea when compared to the control group with physiological pregnancy. CONCLUSION: Supposed increase in various antiphospholipid antibodies (aPLs) levels due to the stress during the short time of admission and a need for a quick medical decision to terminate the pregnancy was not unambiguously proven, but our results are evidently influenced by the current urgent life-saving treatment. |
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Authors:
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Libor Hradecky; Ivan Subrt; Zdenka Ulcova-Gallova |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: American journal of reproductive immunology (New York, N.Y. : 1989) Volume: 62 ISSN: 1600-0897 ISO Abbreviation: Am. J. Reprod. Immunol. Publication Date: 2009 Dec |
Date Detail:
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Created Date: 2009-11-09 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8912860 Medline TA: Am J Reprod Immunol Country: Denmark |
Other Details:
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Languages: eng Pagination: 412-7 Citation Subset: IM |
Affiliation:
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Department of Gynecology and Obstetrics, Charles University and Faculty Hospital, Pilsen, Czech Republic. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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