Document Detail

Urethrography in urethral trauma: tissue reaction to extravasation of contrast dye and iatrogenic infection.
MedLine Citation:
PMID:  7009159     Owner:  NLM     Status:  MEDLINE    
The reaction of periurethral tissue to retrograde urethrography with 30 or 60% contrast dye and/or iatrogenic infection following a sharp, penetrating injury of the urethra was investigated in rabbits. Urine was diverted continuously by tubeless cystostomy throughout the experiment. The local healing processes did not differ from the normal reaction after urethrography with 10 ml 30 or 60% sodium-meglumine-amidotrizoate or instillation of 1--2 . 10(6) E. coli in 10 ml saline. An increased inflammatory reaction was only observed when urethrography and the instillation of E. coli saline was combined, thus increasing the total fluid volume instilled and with it probably also the intraurethral pressure. The results suggest that retrograde urethrography as a diagnostic procedure immediately after an acute urethral trauma is free of adverse effects on the normal healing processes if performed under aseptic standards, with a small volume of contrast dye and as low as instillation pressure as possible.
G Jakse; M Marberger; H J Simonis; K Paulini
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European urology     Volume:  7     ISSN:  0302-2838     ISO Abbreviation:  Eur. Urol.     Publication Date:  1981  
Date Detail:
Created Date:  1981-05-26     Completed Date:  1981-05-26     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  7512719     Medline TA:  Eur Urol     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  178-83     Citation Subset:  IM    
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MeSH Terms
Escherichia coli Infections / complications
Extravasation of Diagnostic and Therapeutic Materials / complications*
Urethra / injuries,  physiopathology,  radiography*
Urethritis / complications*
Wound Healing*

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