Document Detail

Urethral denervation supersensitivity to noradrenaline after radical hysterectomy.
MedLine Citation:
PMID:  7195607     Owner:  NLM     Status:  MEDLINE    
Urethral closure pressure profiles were registered before and during intravenous infusion of noradrenaline in 7 female patients who had undergone radical hysterectomy, and in whom a bladder denervation supersensitivity test to carbachol previously had been positive. Patients who had a completely denervated bladder had a greater rise in maximum urethral pressure during noradrenaline infusion (exceeding 20 cm H2O) than normal subjects (1 to 15 cm H2O). Urethral supersensitivity to noradrenaline may be a promising test in diagnosing damage of the sympathetic nervous innervation of the lower urinary tract.
J Nordling; H H Meyhoff; T Hald; T Gerstenberg; S Walter; N J Christensen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Scandinavian journal of urology and nephrology     Volume:  15     ISSN:  0036-5599     ISO Abbreviation:  Scand. J. Urol. Nephrol.     Publication Date:  1981  
Date Detail:
Created Date:  1981-08-10     Completed Date:  1981-08-10     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0114501     Medline TA:  Scand J Urol Nephrol     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  21-4     Citation Subset:  IM    
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MeSH Terms
Hysterectomy / adverse effects*
Middle Aged
Norepinephrine / pharmacology*
Sympathetic Nervous System / physiopathology
Urethra / drug effects*,  physiopathology
Urinary Bladder / innervation
Urinary Bladder, Neurogenic / diagnosis*,  etiology,  physiopathology
Reg. No./Substance:

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