Document Detail

Urethral cytology in spinal cord injury patients performing intermittent catheterisation.
MedLine Citation:
PMID:  7970852     Owner:  NLM     Status:  MEDLINE    
Local reactions of the urethral wall are known to occur by repeated introduction of a catheter in the urethra. Urethritis was found in 2-19% of patients practising intermittent catheterisation. Although the use of catheters of smaller size and the liberal use of lubricants may prevent urethral irritation and trauma, it was postulated that hydrophilic catheters (LoFric, Astra Tech Ltd, Stroud, England) induce significantly less trauma than PVC catheters because of the binding of the water molecules to the catheter surface which consists of polyvinylpyrrolidone and sodium chloride. Although urethritis and urethral stricture may represent one end of the spectrum of repeated urethral trauma, minor degrees of inflammation need to be quantitatively determined while assessing two different catheters for intermittent catheterisation. The degree of urethral inflammation in patients practising intermittent catheterisation was studied by urethral cytology and staining the smear by Papanicolaou's method. The number of neutrophil polymorphs and epithelial cells in three random high power fields in the urethral smear was counted and the percentage ratio of polymorphs to epithelial cells was calculated. Group 1 comprised 14 patients practising intermittent catheterisation with a PVC catheter and group 2 comprised 17 patients performing intermittent catheterisation with a LoFric catheter. There was no significant difference between the two groups as regards the age, diagnosis, size of the catheter used for intermittent catheterisation and the number of times that they performed catheterisation during a 24 hour period. Urethral cytology revealed a percentage (mean ratio) ratio of polymorphs to epithelial cells of 66 in group 1 and 0.04 in group 2. (< 0.0005).(ABSTRACT TRUNCATED AT 250 WORDS)
S Vaidyanathan; B M Soni; S Dundas; K R Krishnan
Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Paraplegia     Volume:  32     ISSN:  0031-1758     ISO Abbreviation:  Paraplegia     Publication Date:  1994 Jul 
Date Detail:
Created Date:  1994-11-28     Completed Date:  1994-11-28     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  2985038R     Medline TA:  Paraplegia     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  493-500     Citation Subset:  IM    
Mersey Regional Spinal Injuries Centre, Kew, Southport, England.
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MeSH Terms
Catheters, Indwelling
Child, Preschool
Epithelium / pathology
Middle Aged
Neutrophils / physiology
Spinal Cord Injuries / complications*,  pathology
Urethra / microbiology,  pathology*
Urethritis / etiology,  pathology
Urinary Catheterization / adverse effects*,  instrumentation

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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