| Ureaplasma urealyticum cervical colonization as a marker for pregnancy complications. | |
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MedLine Citation:
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PMID: 7698376 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: To determine the clinical significance of cervical colonization with (Ureaplasma urealyticum (Uu) and its possible relationship to pregnancy outcome. METHODS: Cervical cultures for Uu and serum antibodies to Uu were determined in four groups of pregnant women: (1) 117 women who underwent mid-trimester amniocentesis; (2) 47 women with preterm labor and intact membranes; (3) 34 women with preterm premature rupture of membranes; and (4) a control group of 315 healthy women with normal pregnancies. Statistical methods used were the chi-square and Fisher's exact tests. RESULTS: A significant increase in the cervical colonization rate with Uu was detected in all study groups (62%, 77% and 74%, respectively) when compared with the control group (42%). Women at mid-trimester of pregnancy with a positive cervical culture and high levels of antibodies, had a higher rate of pregnancy complications than those with a negative culture and absence of antibodies (62 vs. 28%, respectively; P = 0.0006). CONCLUSION: Cervical colonization with Uu when associated with elevated titers of antibodies to Uu, may serve as a marker for the identification of a subpopulation of women who are at high risk for the development of pregnancy complications. |
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Authors:
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S Horowitz; J Horowitz; M Mazor; A Porath; M Glezerman |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics Volume: 48 ISSN: 0020-7292 ISO Abbreviation: Int J Gynaecol Obstet Publication Date: 1995 Jan |
Date Detail:
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Created Date: 1995-05-04 Completed Date: 1995-05-04 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0210174 Medline TA: Int J Gynaecol Obstet Country: IRELAND |
Other Details:
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Languages: eng Pagination: 15-9 Citation Subset: IM |
Affiliation:
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Department of Microbiology and Immunology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beersheva, Israel. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Antibodies, Bacterial / analysis Cervix Uteri / microbiology* Cross-Sectional Studies Enzyme-Linked Immunosorbent Assay Female Humans Mycoplasma / isolation & purification Pregnancy Pregnancy Complications / epidemiology* Pregnancy Complications, Infectious / diagnosis*, epidemiology Pregnancy Outcome / epidemiology* Risk Factors Ureaplasma Infections / diagnosis*, epidemiology Ureaplasma urealyticum / immunology, isolation & purification* |
| Chemical | |
Reg. No./Substance:
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0/Antibodies, Bacterial |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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