Document Detail

Ureaplasma: pathogen or passenger in neonatal meningitis?
MedLine Citation:
PMID:  19910840     Owner:  NLM     Status:  MEDLINE    
The significance of Ureaplasma species as pathogens in neonatal meningitis remains contentious. Using an illustrative case of a premature infant with Ureaplasma parvum meningitis, confirmed by cerebrospinal fluid cultures and both specific and 16s rDNA polymerase chain reaction, we discuss the epidemiology of Ureaplasma species, the difficulties involved in diagnosis and establishing pathogenicity, and the challenges in defining appropriate treatment.
Vanessa Clifford; Marc Tebruegge; Neil Everest; Nigel Curtis
Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Pediatric infectious disease journal     Volume:  29     ISSN:  1532-0987     ISO Abbreviation:  Pediatr. Infect. Dis. J.     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2009-12-29     Completed Date:  2010-02-26     Revised Date:  2010-12-08    
Medline Journal Info:
Nlm Unique ID:  8701858     Medline TA:  Pediatr Infect Dis J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  60-4     Citation Subset:  IM    
Infectious Diseases Unit, Department of General Medicine, Royal Children's Hospital Melbourne, Parkville, Victoria, Australia.
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MeSH Terms
Anti-Bacterial Agents / pharmacology,  therapeutic use
Cerebrospinal Fluid / microbiology
DNA, Bacterial / chemistry,  genetics
DNA, Ribosomal / chemistry,  genetics
Infant, Newborn
Meningitis, Bacterial / diagnosis*,  drug therapy,  epidemiology,  microbiology*
Microbial Sensitivity Tests
RNA, Ribosomal, 16S / genetics
Sequence Analysis, DNA
Ureaplasma / genetics,  isolation & purification*,  pathogenicity
Ureaplasma Infections / diagnosis*,  drug therapy,  epidemiology,  microbiology*
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/DNA, Bacterial; 0/DNA, Ribosomal; 0/RNA, Ribosomal, 16S
Comment In:
Pediatr Infect Dis J. 2010 Dec;29(12):1154   [PMID:  21099657 ]

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