Document Detail

Uranium content of blood, urine and hair of exposed and non-exposed persons determined by radiochemical neutron activation analysis, with emphasis on quality control.
MedLine Citation:
PMID:  1785047     Owner:  NLM     Status:  MEDLINE    
Recent reviews have highlighted the diversity (and sparsity) of data for uranium concentrations in body fluids, bone and soft tissues, and it is unclear to what extent this reflects genuine geographical or biological variations. In the present work, a very sensitive radiochemical neutron activation analysis technique (detection limit, 1-2pg g-1) was applied to an exploratory study of uranium levels in hair, urine and blood of non-exposed and occupationally exposed persons. Since quality control in much previous work has been somewhat neglected, this aspect was emphasized by the use of a wide range of suitable reference materials, by standard addition experiments, and by care in sampling and sample handling. For controls, typical levels found in hair, urine and blood were 10 ng g-1, 10 and 5 ng l-1, respectively. The urine values correspond to the lower end of the literature data, while for blood our value is about two orders of magnitude lower than the presently quoted level. In the case of occupationally exposed persons, it was found that hair shows some promise as an indicator of exposure.
A R Byrne; L Benedik
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Science of the total environment     Volume:  107     ISSN:  0048-9697     ISO Abbreviation:  Sci. Total Environ.     Publication Date:  1991 Sep 
Date Detail:
Created Date:  1992-03-16     Completed Date:  1992-03-16     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0330500     Medline TA:  Sci Total Environ     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  143-57     Citation Subset:  IM    
J. Stefan Institute, University of Ljubljana, Slovenia, Yugoslavia.
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MeSH Terms
Hair / chemistry*
Neutron Activation Analysis / methods,  standards
Occupational Exposure*
Reference Values
Uranium / analysis*,  blood,  urine
Reg. No./Substance:

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