Document Detail

An Upward Trend in the Age-Specific Incidence Patterns for Mantle Cell Lymphoma in the US.
MedLine Citation:
PMID:  23350889     Owner:  NLM     Status:  Publisher    
Abstract Although an increased incidence of mantle cell lymphoma (MCL) has been reported, age-specific incidence patterns have not been described. Further analyses could inform investigation into the etiology of this disease. We conducted an epidemiologic study using the 13 SEER registries to evaluate MCL incidence from 1992 through 2009. We calculated the proportional changes in the incidence of MCL for subpopulations defined by age, race, and gender over time and the racial/ethnic and gender disparities. We observed a 130.9% increase MCL incidence from 1992-1994 to 2005-2009. The increase was strongest for males (199.0%) and for whites (153.0%). The incidence increased 161%, 200%, 398%, and 429% from 1992-94 to 2005-09 in white men ages 50-59, 60-69, 70-79, and 80+, respectively, whereas the increase in white females was 86%, 82%, 50%, and 193% in the corresponding age groups. We observed a male-to-female incidence rate ratio (IRR) of 2.65 and a white-to-black IRR of 2.21. Our analysis confirmed significant increases in MCL, and illustrated that the incidence is increasing more rapidly in elderly persons, particularly in white males. We also identified novel age-specific temporal trends by race/ethnicity and sex. In addition, we found that the gender and white-to-black disparities have grown over time. Our findings may impact MCL etiologic investigation and treatment research.
Briseis Aschebrook-Kilfoy; Donne Bennett D Caces; Nicholas J Ollberding; Sonali M Smith; Brian C-H Chiu
Related Documents :
25066339 - Effects of silver nanoparticles exposure in the mussel mytilus galloprovincialis.
24371819 - Analysis of the anticancer phytochemicals in andrographis paniculata nees. under salini...
19482799 - Beliefs and social norms about sildenafil citrate (viagra) misuse and perceived consequ...
20840209 - Online video game addiction: identification of addicted adolescent gamers.
2265589 - The prevalence and self-reported consequences of cocaine use: an exploratory and descri...
7994889 - Oral squamous cell cancer in non-users of tobacco and alcohol.
6641779 - Can age-related deficits in spatial memory be attenuated through the use of verbal coding?
2427459 - Side-effects of sodium valproate, mainly related to its hepatic and pancreatic toxicity.
8404839 - Evaluation of workload in air traffic controllers.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-28
Journal Detail:
Title:  Leukemia & lymphoma     Volume:  -     ISSN:  1029-2403     ISO Abbreviation:  Leuk. Lymphoma     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9007422     Medline TA:  Leuk Lymphoma     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Prediction of early allograft dysfunction using serum phosphorus level in living donor liver transpl...
Next Document:  Vascular endothelial growth factor expression in acute myeloid leukemia: a biomarker ready for prime...