| Uptake of synthetic polynucleotides by competent cells of Bacillus subtilis. | |
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MedLine Citation:
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PMID: 4992366 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A survey was made of the capacity of competent cells of Bacillus subtilis to take up synthetic polynucleotides. Polydeoxyribonucleotides but not polyribonucleotides are taken up by the cells. Both types of polynucleotide failed to compete with transforming deoxyribonucleic acid in the transformation assay whereas both stimulated amino acid incorporation. The latter phenomenon appears to be nonspecific as there is no correlation between the codon composition of the polynucleotides employed and the amino acids whose incorporation was stimulated. |
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Authors:
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O Ciferri; S Barlati; J Lederberg |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of bacteriology Volume: 104 ISSN: 0021-9193 ISO Abbreviation: J. Bacteriol. Publication Date: 1970 Nov |
Date Detail:
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Created Date: 1971-02-09 Completed Date: 1971-02-09 Revised Date: 2010-09-10 |
Medline Journal Info:
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Nlm Unique ID: 2985120R Medline TA: J Bacteriol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 684-8 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Amino Acids
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metabolism Bacillus subtilis / growth & development, metabolism* Bacteriological Techniques Carbon Isotopes Culture Media DNA, Bacterial / metabolism Genetics, Microbial* Polynucleotides / metabolism*, pharmacology Time Factors Transformation, Genetic* / drug effects Tritium |
| Chemical | |
Reg. No./Substance:
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0/Amino Acids; 0/Carbon Isotopes; 0/Culture Media; 0/DNA, Bacterial; 0/Polynucleotides; 10028-17-8/Tritium |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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