Document Detail


Uptake ratio of (19-1311) cholesterol by adrenal glands as observed by a scintigraphic method.
MedLine Citation:
PMID:  1154387     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The adrenal scintigram was performed after administration of [19-131I] cholesterol. A high/low ratio of both adrenal glands was calculated to evaluate whether there is a difference between the left and right sides in adrenal diseases. During scanning, information was stored in a 64 X 64 matrix and then punched out on a computer compatible paper tape. This paper tape was processed with a small digital computer. The areas of interest were selected over adrenal glands. The computer decided mean counts per unit area. After subtraction of background counts, a high/low ratio of adrenal gland was calculated. In five patients with Cushing's syndrome due to bilateral hyperplasia, a high/low ratio ranged from 1.0 to 2.0. In four patients with primary aldosteronism due to adenoma, a high/low ratio ranged from 1.33 to 4.0. This method may be useful to differentiate bilateral hyperplasia from unilateral adrenocortical adenoma.
Authors:
M Nakamura; Y Sawai; S Fukuchi; K Nakajima; M Abe
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Tohoku journal of experimental medicine     Volume:  116     ISSN:  0040-8727     ISO Abbreviation:  Tohoku J. Exp. Med.     Publication Date:  1975 Jun 
Date Detail:
Created Date:  1975-11-05     Completed Date:  1975-11-05     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0417355     Medline TA:  Tohoku J Exp Med     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  191-9     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adenoma / diagnosis
Adolescent
Adrenal Gland Diseases / diagnosis*
Adrenal Gland Neoplasms / diagnosis
Adrenal Glands / metabolism*
Adrenocortical Hyperfunction / diagnosis
Adult
Cholesterol / metabolism*
Computers
Cushing Syndrome / diagnosis
Female
Humans
Hyperaldosteronism / diagnosis
Hyperplasia
Iodine Radioisotopes / diagnostic use
Male
Middle Aged
Pheochromocytoma / diagnosis
Radionuclide Imaging* / methods
Chemical
Reg. No./Substance:
0/Iodine Radioisotopes; 57-88-5/Cholesterol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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