Document Detail

Uptake of isoflurane during clinical anaesthesia. Servo-control of liquid anaesthetic injection into a closed-circuit breathing system.
MedLine Citation:
PMID:  6639825     Owner:  NLM     Status:  MEDLINE    
Twenty-six patients were anaesthetized with isoflurane (Forane) in oxygen using a completely closed-circuit breathing system to which liquid isoflurane was injected. The rate of injection was controlled to maintain the end-tidal concentration at a pre-set value (1.5% = 1.3 MAC). The rate of injection of anaesthetic was recorded and from the data the uptake of anaesthetic by the patient was measured. It was found to average 44.5 ml of vapour at 2 min, 23.7 ml at 10 min and 19.4 ml at 30 min. Attempts were made to correlate the data with anthropometric measurements.
A C O'Callaghan; D W Hawes; J A Ross; D C White; R T Wloch
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  British journal of anaesthesia     Volume:  55     ISSN:  0007-0912     ISO Abbreviation:  Br J Anaesth     Publication Date:  1983 Nov 
Date Detail:
Created Date:  1984-01-07     Completed Date:  1984-01-07     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372541     Medline TA:  Br J Anaesth     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1061-4     Citation Subset:  IM    
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MeSH Terms
Anesthesia, Inhalation / methods*
Body Constitution
Drug Administration Schedule
Isoflurane / administration & dosage,  metabolism*
Methyl Ethers / metabolism*
Middle Aged
Skinfold Thickness
Tidal Volume
Time Factors
Reg. No./Substance:
0/Methyl Ethers; 26675-46-7/Isoflurane; 7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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