| Uptake and intracellular distribution of lanthanum. | |
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MedLine Citation:
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PMID: 6159848 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The present investigation of the cellular distribution of lanthanum was undertaken in order to control the validity of the "Lanthanum method" used for the study of the cell calcium compartments. The presence of lanthanum was evaluated in the isolated guinea-pig heart and its subcellular fractions perfused with a lanthanum-containing Tyrode solution. Lanthanum was determined by instrumental neutron activation analysis. Under the adopted experimental conditions (30-min incubation in the presence of 12.5 microM lanthanum), lanthanum is carried across the cell membrane and is taken up by subcellular organelles. These results confirm the limited validity of investigations based on of the "Lanthanum method". |
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Authors:
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M C Chiari; V C Crespi; L Favalli; F Piccinini |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Archives internationales de physiologie et de biochimie Volume: 88 ISSN: 0003-9799 ISO Abbreviation: Arch. Int. Physiol. Biochim. Publication Date: 1980 Aug |
Date Detail:
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Created Date: 1981-01-16 Completed Date: 1981-01-16 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0405355 Medline TA: Arch Int Physiol Biochim Country: BELGIUM |
Other Details:
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Languages: eng Pagination: 225-30 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Biological Transport Female Guinea Pigs Heart / physiology* Heart Rate / drug effects Lanthanum / metabolism*, pharmacology Male Myocardial Contraction / drug effects Myocardium / metabolism* Subcellular Fractions / metabolism |
| Chemical | |
Reg. No./Substance:
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7439-91-0/Lanthanum |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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