| Uptake of enflurane and isoflurane during spontaneous and controlled ventilation. | |
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MedLine Citation:
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PMID: 1534467 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The uptake of enflurane and of isoflurane were studied in forty patients during anaesthesia with nitrous oxide using either spontaneous or controlled ventilation. A Douglas bag method was used in combination with low fresh gas flows to a circle system and constant end-tidal anaesthetic concentration. The mean enflurane uptake rates were between 24 and 14 ml.70kg-1.min-1 between 10 and 60 minutes. Corresponding isoflurane uptake rates were between 15 and 8 ml. 70 kg-1.min-1. The initial uptake rates were lower than expected from "the square root of time concept". During spontaneous ventilation, the anaesthetic uptake rates were similar or even higher than corresponding rates during controlled ventilation in spite of lower minute ventilation volumes. |
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Authors:
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J P Bengtson; A Bengtsson; O Stengvist |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Anaesthesia and intensive care Volume: 20 ISSN: 0310-057X ISO Abbreviation: Anaesth Intensive Care Publication Date: 1992 May |
Date Detail:
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Created Date: 1992-06-29 Completed Date: 1992-06-29 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0342017 Medline TA: Anaesth Intensive Care Country: AUSTRALIA |
Other Details:
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Languages: eng Pagination: 191-5 Citation Subset: IM |
Affiliation:
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Department of Anaesthesia and Intensive Care, Sahlgren Hospital, University of Göteborg, Sweden. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Anesthesia, Inhalation* / instrumentation Anesthesia, Intravenous Calibration Carbon Dioxide / analysis Enflurane / administration & dosage, pharmacokinetics* Equipment Design Female Humans Isoflurane / administration & dosage, pharmacokinetics* Lung / metabolism Male Nitrous Oxide / administration & dosage, analysis Oxygen / administration & dosage, analysis Respiration* Respiration, Artificial* Rheology Thiopental / administration & dosage Tidal Volume |
| Chemical | |
Reg. No./Substance:
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10024-97-2/Nitrous Oxide; 124-38-9/Carbon Dioxide; 13838-16-9/Enflurane; 26675-46-7/Isoflurane; 76-75-5/Thiopental; 7782-44-7/Oxygen |
| Comments/Corrections | |
Comment In:
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Anaesth Intensive Care. 1992 Nov;20(4):543
[PMID:
1463208
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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