Document Detail


Uptake and dissimilation of glycerol by wild type and glycerol nonutilizing strains of Neurospora crassa.
MedLine Citation:
PMID:  6222238     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Seven mutant strains defective for utilization of glycerol, glyceraldehyde or dihydroxyacetone were isolated. One strain was deficient for NAD-linked glycerol-3-phosphate dehydrogenase, two for glycerol kinase, and four had no detected enzymatic deficiency, although one of the latter strains was deficient in glycerol uptake. Glycerol uptake was increased by incubation in glycerol, glycerol-3-phosphate, erythritol, and propanediol, and was protein-mediated below 0.14 mM glycerol, but at higher concentrations free diffusion predominated. Glycerol uptake was decreased by cycloheximide and was more sensitive to sodium azide than to iodoacetate.
Authors:
J E Pyle; H B Howe
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Molecular & general genetics : MGG     Volume:  189     ISSN:  0026-8925     ISO Abbreviation:  Mol. Gen. Genet.     Publication Date:  1983  
Date Detail:
Created Date:  1983-07-08     Completed Date:  1983-07-08     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0125036     Medline TA:  Mol Gen Genet     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  166-8     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Glycerol / genetics,  metabolism*
Glycerol Kinase / genetics
Glycerolphosphate Dehydrogenase / genetics
Mutation
Neurospora / metabolism*
Neurospora crassa / genetics,  metabolism*
Chemical
Reg. No./Substance:
56-81-5/Glycerol; EC 1.1.-/Glycerolphosphate Dehydrogenase; EC 2.7.1.30/Glycerol Kinase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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