Document Detail

Uptake of desflurane during anaesthesia.
MedLine Citation:
PMID:  8669563     Owner:  NLM     Status:  MEDLINE    
The amount of desflurane required to maintain an end-expired concentration of 8% was measured in 30 ASA 1 and 2 patients undergoing elective spinal surgery. The anaesthetic was administered using a computer-controlled closed circle system. After an initial period during which the expired concentration of desflurane was stabilised (4 min) the rate of uptake showed a bi-exponential decline. Mean cumulative usage of desflurane was 10.1 ml of liquid at 30 min, 14.8 ml at 60 min, 25.4 ml at 120 min, 35.8 at 180 min.
T J Walker; M K Chakrabarti; G G Lockwood
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Anaesthesia     Volume:  51     ISSN:  0003-2409     ISO Abbreviation:  Anaesthesia     Publication Date:  1996 Jan 
Date Detail:
Created Date:  1996-08-05     Completed Date:  1996-08-05     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370524     Medline TA:  Anaesthesia     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  33-36     Citation Subset:  AIM; IM    
Department of Anaesthesia, Hammersmith Hospital, London.
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MeSH Terms
Anesthesia, Closed-Circuit
Anesthetics, Inhalation / pharmacokinetics*
Breath Tests
Isoflurane / analogs & derivatives*,  pharmacokinetics
Middle Aged
Spinal Diseases / surgery
Surgical Procedures, Elective
Reg. No./Substance:
0/Anesthetics, Inhalation; 26675-46-7/Isoflurane; 57041-67-5/desflurane
Comment In:
Anaesthesia. 1997 May;52(5):502-3   [PMID:  9165975 ]

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