Document Detail


Upper and lower urinary tract infection caused by Klebsiella pneumoniae serotype K2 and CTX-M-15 beta-lactamase-producing serotype K1: a case report and characterization of serum killing resistance.
MedLine Citation:
PMID:  18065678     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
CTX-M-15 beta-lactamase-producing Klebsiella pneumoniae serotype K1 was isolated from a patient with fatal upper urinary tract infection (UTI) complicated by sepsis caused by K. pneumoniae serotype K2. Transfer of a CTX-M-15 beta-lactamase plasmid from the K1 to the K2 strain was observed. However, plasmid acquisition by the K2 strain did not occur in vivo, suggesting that the K1 strain might not have contributed directly to the upper UTI. In addition, effects of K serotypes and plasmid acquisition on K. pneumoniae serum resistance were examined.
Authors:
Noriyuki Nagano; Christophe Cordevant; Yukiko Nagano
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of medical microbiology     Volume:  57     ISSN:  0022-2615     ISO Abbreviation:  J. Med. Microbiol.     Publication Date:  2008 Jan 
Date Detail:
Created Date:  2007-12-10     Completed Date:  2008-05-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0224131     Medline TA:  J Med Microbiol     Country:  England    
Other Details:
Languages:  eng     Pagination:  121-4     Citation Subset:  IM    
Affiliation:
Medical Microbiology Laboratory, Funabashi Municipal Medical Center, 1-21-1 Kanasugi, Fubanashi, Chiba 273-8588, Japan. naganoyn@d3.dion.ne.jp
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MeSH Terms
Descriptor/Qualifier:
Aged
Anti-Bacterial Agents / pharmacology,  therapeutic use
Blood Bactericidal Activity / immunology*
Humans
Klebsiella Infections / mortality,  physiopathology
Klebsiella pneumoniae / drug effects,  enzymology,  genetics,  isolation & purification*
Male
Urinary Tract Infections / microbiology*
beta-Lactamases / genetics,  metabolism*
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents; EC 3.5.2.-/beta-lactamase CTX-M-15; EC 3.5.2.-/beta-lactamase K1; EC 3.5.2.6/beta-Lactamases

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