| Upper gastrointestinal bleeding after hip and knee arthroplasty. | |
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MedLine Citation:
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PMID: 16539204 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The use of nonsteroidal anti-inflammatory drugs (NSAIDs) and anticoagulants increases the risk of upper gastrointestinal bleeding. This article assesses its incidence in patients undergoing hip and knee arthroplasty. A single-center, retrospective study was conducted on 100 consecutive hip and 100 consecutive knee arthroplasties performed at the Victoria Infirmary, Glasgow, between 1998 and 2000. Sixty-three percent of patients were women with a mean age of 74. Fifty-four percent of patients received NSAIDs and all patients received anticoagulants perioperatively. Four and a half percent of patients had upper gastrointestinal bleeding postoperatively. We believe that the incidence of upper gastrointestinal bleeding as a complication is underestimated and recommend gastro-protective agents in the perioperative period for patients on NSAIDs. |
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Authors:
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Sunil Sharma |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Orthopedics Volume: 29 ISSN: 0147-7447 ISO Abbreviation: Orthopedics Publication Date: 2006 Mar |
Date Detail:
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Created Date: 2006-03-16 Completed Date: 2006-07-20 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7806107 Medline TA: Orthopedics Country: United States |
Other Details:
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Languages: eng Pagination: 255-7 Citation Subset: IM |
Affiliation:
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Glasgow Royal Infirmary, Glasgow, Scotland, United Kingdom. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Anti-Inflammatory Agents, Non-Steroidal / administration & dosage, adverse effects Anticoagulants / administration & dosage, adverse effects Arthroplasty, Replacement, Hip* Arthroplasty, Replacement, Knee* Aspirin / administration & dosage, adverse effects Barrett Esophagus / diagnosis, drug therapy Duodenal Ulcer / diagnosis, drug therapy Endoscopy, Gastrointestinal Female Gastrointestinal Hemorrhage / etiology* Heparin, Low-Molecular-Weight / administration & dosage, adverse effects Humans Length of Stay Male Middle Aged Postoperative Complications* Proton Pumps / antagonists & inhibitors Retrospective Studies Stomach Ulcer / diagnosis, drug therapy Venous Thrombosis / prevention & control |
| Chemical | |
Reg. No./Substance:
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0/Anti-Inflammatory Agents, Non-Steroidal; 0/Anticoagulants; 0/Heparin, Low-Molecular-Weight; 0/Proton Pumps; 50-78-2/Aspirin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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