Document Detail

Upper gastrointestinal abnormalities and Helicobacter pylori in Beh?et's disease.
MedLine Citation:
PMID:  20064169     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: There are few published clinical trials concerning upper gastrointestinal (GI) involvement in Beh?et's disease (BD), and most have been performed on patients with upper GI tract symptoms. AIM: We sought to determine whether routine endoscopy is indicated in asymptomatic patients with BD and whether Helicobacter pylori plays a role in the pathogenesis of BD. METHODS: Forty consecutive patients with BD and 40 age- and gender-matched controls with tinea pedis were studied. All patients underwent fiberoptic esophagogastroduodenoscopy. Urea breath test was used to identify H. pylori. RESULTS: Abnormalities were noted in 37 patients (93%): hiatal hernia (53%), antral gastritis (33%), pan-gastritis (23%), gastric ulceration (8%), and duodenal ulceration (8%). Helicobacter pylori was found in 26 patients (65%) with BD and in 28 controls (70%) (no significant difference by chi-squared test, P > 0.05). We found a high incidence of upper GI abnormalities in BD, but the abnormalities were not specific for the disorder. CONCLUSIONS: Routine endoscopy and screening for H. pylori infection may not be necessary in asymptomatic patients with BD.
Seray K?lc? Cakmak; Atil Cakmak; Ulker G?l; Marlen Sulaimanov; Pelin Bing?l; M Sel?uk Hazinedaro?lu
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of dermatology     Volume:  48     ISSN:  1365-4632     ISO Abbreviation:  Int. J. Dermatol.     Publication Date:  2009 Nov 
Date Detail:
Created Date:  2010-01-12     Completed Date:  2010-03-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0243704     Medline TA:  Int J Dermatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1174-6     Citation Subset:  IM    
2nd Dermatology Clinic, Ankara Numune Education and Research Hospital, Ministry of Health, and General Surgery Department, Ankara University School of Medicine, Ankara, Turkey.
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MeSH Terms
Behcet Syndrome / epidemiology*
Endoscopy, Digestive System
Gastritis / epidemiology*,  microbiology,  pathology
Helicobacter Infections / epidemiology*,  pathology
Helicobacter pylori*
Hernia, Hiatal / epidemiology,  pathology
Middle Aged
Stomach Ulcer / epidemiology,  microbiology,  pathology
Young Adult

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