Document Detail

Upper esophageal sphincter and pharyngoesophageal motor function in infants with and without gastroesophageal reflux.
MedLine Citation:
PMID:  6862154     Owner:  NLM     Status:  MEDLINE    
Upper esophageal sphincter and pharyngeal motor function were assessed in 16 infants with gastroesophageal reflux and 11 age-matched control infants. Resting upper esophageal sphincter pressure in gastroesophageal reflux infants was 26.6 +/- 10.0 cmH2O (means +/- SD) and was similar to that of control infants (28.9 +/- 10.0 cmH2O). Pharyngeal contraction amplitude, duration, and velocity were the same in control and reflux subjects. A minor degree of incoordination between pharyngeal contraction and upper esophageal sphincter relaxation was noted in 2 control subjects and 2 infants with gastroesophageal reflux. Esophageal acidification produced an increase in mean upper esophageal sphincter resting pressure of 10.0 cmH2O in controls and 11.1 cmH2O in reflux patients.
J M Sondheimer
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Gastroenterology     Volume:  85     ISSN:  0016-5085     ISO Abbreviation:  Gastroenterology     Publication Date:  1983 Aug 
Date Detail:
Created Date:  1983-08-11     Completed Date:  1983-08-11     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0374630     Medline TA:  Gastroenterology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  301-5     Citation Subset:  AIM; IM    
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MeSH Terms
Esophagogastric Junction / physiopathology*
Gastroesophageal Reflux / physiopathology*
Gastrointestinal Motility*
Hydrogen-Ion Concentration
Muscle Contraction
Muscle, Smooth
Pharynx / physiopathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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