Document Detail

Updates in perioperative coagulation: physiology and management of thromboembolism and haemorrhage.
MedLine Citation:
PMID:  15220183     Owner:  NLM     Status:  MEDLINE    
Understanding of blood coagulation has evolved significantly in recent years. Both new coagulation proteins and inhibitors have been found and new interactions among previously known components of the coagulation system have been discovered. This increased knowledge has led to the development of various new diagnostic coagulation tests and promising antithrombotic and haemostatic drugs. Several such agents are currently being introduced into clinical medicine for both the treatment or prophylaxis of thromboembolic disease and for the treatment of bleeding. This review aims to elucidate these new concepts and to outline some consequences for clinical anaesthesia and perioperative medicine.
T Bombeli; D R Spahn
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Publication Detail:
Type:  Journal Article; Review     Date:  2004-06-25
Journal Detail:
Title:  British journal of anaesthesia     Volume:  93     ISSN:  0007-0912     ISO Abbreviation:  Br J Anaesth     Publication Date:  2004 Aug 
Date Detail:
Created Date:  2004-07-14     Completed Date:  2004-09-28     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0372541     Medline TA:  Br J Anaesth     Country:  England    
Other Details:
Languages:  eng     Pagination:  275-87     Citation Subset:  IM    
Coagulation Laboratory, Division of Haematology, University Hospital of Zürich, Sternwartstrasse 14, CH-8091 Zürich, Switzerland.
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MeSH Terms
Blood Coagulation
Blood Loss, Surgical / prevention & control*
Fibrinolytic Agents / therapeutic use
Hemostasis, Surgical / methods*
Perioperative Care / methods
Risk Assessment / methods
Thromboembolism / therapy*
Reg. No./Substance:
0/Fibrinolytic Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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